All functions |
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Center log ratio normalisation |
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Tune ncomp using cross-validation. |
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Tune nfeat using cross-validation. |
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Keep common genes of two SingleCellExperiment objects. |
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PhiSpace continuous phenotyping |
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PhiSpace using a single reference |
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Apply rank transform to a gene by cell matrix. |
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Rank transform of a |
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Compute regression model using selected features. |
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Visualising features (eg gene expression), metadata (eg cell type) or reducedDim component (eg PhiSpace cell type score) in 2D tissue space. |
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Align clustering results. |
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Convert a matrix to sparse metrix. |
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Plot formatting for presentation and publication |
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Create cell type correlation matrices |
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Calculate classification errors. |
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Convert discrete annotations to dummy variable matrices. |
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Convert discrete annotations to dummy variable matrices. |
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Compute UMAP. |
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Double center a matrix by column and row means, resulting in a new matrix with zero row and column means. |
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Dicretise soft annotation to labels. |
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Compute different errors for cross-validation. |
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Calculate errors for the cross-validation for selecting nfeat. |
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Principal component analysis (PCA) based on partial singular value decomposition (SVD). |
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Plot loadings of dimension reduction as bar plot. |
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Relative counts normalisation. |
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Score matrix plot |
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Multivariate regression via principal component analysis (PCA) or partial least squares (PLS). |
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Normalise PhiSpace phenotypic scores by row or by column. |
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Soft phenotyping of query assay. |
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Plot PhiSpace scores as a heatmap |
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Plot Sankey diagram for two classification results. |
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Plot Sankey diagram for three hard classification results. |
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Converting single cells to pseudo-bulks. |
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Turn a matrix to a data.frame withe newly defined colnames. |
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Run scran normalisation |
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Select nfeat top features from each column (label) of impScores |
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Create partitions of data for cross-validation. |
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Subsample from a sce object |
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Translate cell type labels from finer to coarser according to a dictionary. |
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Title |
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Minimal quality control (QC): remove features with all zero values. |